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April 30, 2016
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ARKIVOC is an international journal of organic chemistry completely free electronically world wide.
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Arkat USA, Inc. is a non profit foundation existing to help chemists throughout the world with special emphasis on international cooperation and developing countries.
Arkivoc manuscript activity / Traffic at arkat-usa.org

MS in Hand Apr 1st, 2016: 72. Received 37; Published 11; Rejected 17. In Hand End of Apr 81;
Manuscripts in Hand Jan 1st, 2016: 65; Received 146; Published 30; Rejected 99.

Access hits, April: 637,938 from 94,677 visitors;
2016 to date: 2,337,095 from 373,814 visitors.

Graphical Abstracts
of Manuscripts Published in Arkivoc During April 2016
Arkivoc 2016 Part (i): Special Issue 'Reviews and Accounts'
Advances in structural modifications of celastrol (16-9540LR) [pp. 172-182]
Xiao-hua Cai, Jun Jin and Meng Huiyuan He
Full Text: PDF (165K)
Methods for synthesis of N-heterocyclyl/heteroaryl- α-aminophosphonates and α-(azaheterocyclyl)phosphonates (16-9519LR) [pp. 183-211]
Reda M. Abdel-Rahman, Tarik E. Ali and Somaia M. Abdel-Kariem
Full Text: PDF (435K)
Arkivoc 2016 Part (iii): General Papers
A simple one-pot synthesis of new 9-aroyl-3,4,6,7,9,10-hexahydro-1,8(2H,5H)-acridinediones (16-9445UP) [pp. 262-270]
Ahmad Poursattar Marjani, Jabbar Khalafy and Sahar Mahmoodi
Full Text: PDF (608K)
Supplementary Material: PDF (2,363K)
In situ formed tert-butyl hypoiodite as an efficient oxidant for rapid, room temperature, metal-free aromatization of Biginelli 3,4-dihydropyrimidin-2(1H)-ones under basic conditions (16-9562IP) [pp. 271-286]
Danijela Lesjak Kolarović, Vladimir Vinković and Mladen Litvić
Full Text: PDF (230K)
Synthesis of spiro-1,2,4-triazole-3-thiones from cycloalkanone thiosemicarbazones, and formation of a cyclic 1,2-dithione (16-9425BP) [pp. 287-303]
Alaa A. Hassan, Shaaban K. Mohamed, Nasr K. Mohamed, Kamal M. A. El-Shaieb, Ahmed T. Abdel-Aziz, Joel T. Mague and Mehmet Akkurt
Full Text: PDF (1,366K)
Supplementary Material: PDF (801K)
Bis(indoline-2,3-diones): versatile precursors for novel bis(2',6'-dimethyl-2-oxo-1'H-spiro[indoline-3,4'-pyridine]-3',5'-dicarbonitrile) derivatives (16-9423GP) [pp. 304-312]
Amr M. Abdelmoniem, Ahmed H. M. Elwahy and Ismail A. Abdelhamid
Full Text: PDF (926K)
Supplementary Material: PDF (1,972K)
Aluminum triflate catalyzed Povarov reaction for the synthesis of pyranotetrahydroquinolines (16-9447IP) [pp. 313-324]
Mokela S. Sokamisa, Yonela M. Nyondlo and Henok H. Kinfe
Full Text: PDF (130K)
Supplementary Material: PDF (9,737K)
Reactions of resorcinarene with N,N-dimethylcarbamoyl and N,N-dimethylthiocarbamoyl chlorides. Factors affecting the process performance (16-9492JP) [pp. 325-338]
Vera Ivanovna Maslennikova, Anastasia V. Burikhina, Olga S. Serkova, Dmitrii V. Tarasenko, Irina I. Levina and Anastasia V. Gorlova
Full Text: PDF (232K)
Total synthesis of 5-hydroxyomeprazole (16-9501GP) [pp. 339-351]
Romualdas Striela, Gintaras Urbelis, Jurgis Sūdžius, Sigitas Stončius, Rita Mažeikaitė and Linas Labanauskas
Full Text: PDF (265K)
Optimization of conditions for the reaction between β-lactam carbenes and 3,6-di-(2-thienyl)tetrazine (16-9524ZP) [pp. 352-359]
Xiuqing Yao and Xiaorong Wang
Full Text: PDF (185K)
New V-shaped push-pull systems based upon 4,5-di(hetero)aryl substituted pyrimidines: their synthesis and application for the detection of nitroaromatic explosives (16-9470NP) [pp. 360-373]
Egor V. Verbitskiy, Anna A. Baranova, Kseniya I. Lugovik, Konstantin O. Khokhlov, Ekaterina M. Cheprakova, Gennady L. Rusinov, Oleg N. Chupakhin and Valery N. Charushin
Full Text: PDF (282K)
Supplementary Material: PDF (600K)
Individual Issues of Arkivoc
No issues were completed during April 2016.
The following issues were closed during April 2016:

2016 Part (iii): General Papers
The following new issues were initiated during April 2016:

2016 Part (iv): General Papers
The 17th Annual Florida Heterocyclic and Synthetic Conference

The 17th Annual Florida Heterocyclic and Synthetic Conference, FloHet-2016, was held at the University of Florida in Gainesville, from February 28th to March 2nd. Eleven plenary lectures, a short course, 54 invited lectures, 36 posters were presented, and a small exposition was held. The next FloHet Conference will be held at the University of Florida from March 4th to 7th, 2018.

Plenary Lectures
Steven Ley, Cambridge University, UK Katritzky Memorial Lecture
"Machine-Assisted Organic Synthesis"
Aaron Aponick , University of Florida, US
"StackPhos: from Structural Curiosity to Enantioselective Catalysis"
Martin Burke, University of Illinois, USA
"Making Molecular Prosthetics with a Small Molecule Synthesizer"
Naoto Chatani, Osaka University, Japan
"Nickel-Catalyzed Functionalization of C-H Bonds Utilizing a New Chelation System"
Abigail Doyle, Princeton University, USA
"New Directions in Nickel-Catalyzed Cross Coupling"
Sabine Flitsch, University of Manchester, UK
"Enzyme Cascades for the Stereoselective Synthesis of Heterocycles"
Nicholas Meanwell, Bristol-Myers Squibb, USA
"The Discovery and Development of Direct Acting Inhibitors of Hepatitis C Virus"
David Mitchell, Eli Lilly, USA
"Designing and applying practical process synthesis methodologies for aminopyrazoles"
John Porco, Boston University, USA
"Chemical Synthesis and Biological Studies of Antitumor Natural Products"
Richmond Sarpong, UC Berkeley, USA
"Strategies and Tactics for the Synthesis of Complex Alkaloids"
David Williams, Indiana University, USA
"Strategies Toward the Synthesis of Polycyclic Alkaloids"

Short Course
Gordon Gribble, Dartmouth College, USA
A Cook’s Tour of Lithium, Palladium, Magnesium, Gold, and Copper in Heterocyclic Chemistry

We thank our Sponsors, Advertisers and Exhibitors; Advion, BioTools, CEM, EigenChem, IUPAC, J & K, Oakwood Products, Rieke Metals, The Royal Society of Chemistry, SynQuest Laboratories, Synthonix, Thieme Chemistry for their generous support.

With over 20 years of mass spectrometry and chemistry expertise, Advion offers the expression family of compact mass spectrometers designed for the chemist. The affordability, small size and ease-of-use make them ideal for use directly at the chemist’s bench, giving immediate answers and informed decisions instead of waiting in line at a central analytical service laboratory.

The Alachua County Visitors and Convention Bureau "Visit Gainesville" is the source for planning a visit to Gainesville. They provide support for this conference through the Tourist Development Conference Grant, Fall 2015.

BioTools specializes in structure elucidation of chiral molecules. The first company to commercialize VCD (Vibrational Circular Dichroism) and ROA (Raman Optical Activity), BioTools provides instrumentation and services. VCD is the fastest growing technique for determination of absolute configuration of chiral molecules and is used worldwide by all top pharmaceutical companies, regulatory agencies and academia.

CEM is a leading global provider of microwave laboratory systems that provide fast, reproducible results in rugged, flexible platforms. The Discover® SP System for sequential synthesis and the MARS 6 for parallel synthesis and scale up offer unmatched versatility with options for automation, peptide synthesis, low-temperature chemistries, gas-addition, and more.

EigenChem Technologies Inc. provides contract research and contract manufacturing services with a specialization in the synthesis of organic chemicals for pharmaceutical, cosmetic, and nutraceutical industries. We have knowledge and skills at performing complex, multi-step synthesis and delivering solutions for one-of-a-kind chemistry-related problems.

J & K Scientific
As one of the world’s leading chemical manufacturers, J&K Scientific provides thousands of ultrafine chemicals for research in organic chemistry, analytical chemistry, life science and materials science, as well as a wide range of specialty chemical products for both science and industry.

Oakwood Products, a manufacturer and distributor, supplies research chemicals to the pharmaceutical, agrochemical and materials research communities. The Oakwood product listing contains over 100,000 items, including many unique building blocks and reactive intermediates.
Please visit us at www.oakwoodchemical.com

Rieke Metals Inc. began in 1991 with its foundation in 40+ years of active metal research. The company sells active Rieke Zinc and Magnesium, Grignard and Organozinc reagents, fine organic chemicals and organic semi-conducting polymers/monomers. Headquartered in Lincoln, Nebraska, the facility personally manufactures over 10,000 research compounds.

SynQuest specializes in fluorinated organic and inorganic chemicals, providing a creative and innovative range of building blocks, reagents and compressed and liquefied gases. We offer chemical services designed to expedite your research from conception to pilot quantities.

Synthonix specializes in the medicinal chemistry driven design of novel 3-dimensional building blocks. These compounds are designed to allow our customers access to unexplored chemical space. Our team of scientists includes Ph.D., Masters, and Bachelor level chemists. Synthonix is focused on delivering high quality products and exceptional satisfaction to all of our customers. We have a 10,000 square foot research and manufacturing facility located in Wake Forest, North Carolina.

Thieme Chemistry publishes highly evaluated information about synthetic and general chemistry for professional chemists and advanced students since 1909. Our portfolio includes the well known journals SYNFACTS, SYNLETT and SYNTHESIS, the renowned synthetic methodology reference work Science of Synthesis, RÖMPP, the largest chemical encyclopedia published in German, and monographs.

Forthcoming Conferences

The 27th European Colloquium on Heterocyclic Chemistry (ECHC 2016);

This traditional meeting with a famous history will be held in the beautiful Beurs van Berlage, in the city center of Amsterdam, from July 3 to July 6, 2016. The ECHC2016 covers the field in its full range, from Organic Synthesis, Materials and Catalysis to Chemical Biology and Medicinal Chemistry. We have a great line-up of world renowned speakers.

15th Belgian Organic Synthesis Symposium
July 10-15, 2016 - Antwerp, Belgium

The conference will cover a broad range of timely subjects in the field of organic chemistry. One of the major aims of the BOSS symposia has always been to give young chemists the possibility to attend a high level conference at a reasonable cost, instead of only addressing a small group of highly specialised chemists.

Future Conferences

The 26th International Society of Heterocyclic Chemistry Congress will be held in Regensburg, Germany, 3 to 8 September 2017.

The 18th Florida Heterocyclic and Synthetic Conference (FloHet-2018) will take place at the University of Florida, Gainesville, 4 to 7 March 2018.

New Members
of the Arkivoc Editorial Board of Referees
Dr.. Vijay Kumar
United States
Prof Mohammad Reza Poor Heravi

ARKIVOC - Free Journal of Organic Chemistry