MS in Hand Oct 1^st, 2014: 65. Received 53; Published 7; Rejected 29. In Hand End of Oct 82;
Manuscripts in Hand Jan 1^st, 2014: 81; Received 419; Published 95; Rejected 323.

Access hits, October: 656,677 from 110,472 visitors;
2014 to date: 5,790,387 from 1,100,163 visitors.

Eleven plenary lectures, one short course, 52 invited lectures, 50 posters, and a small exposition are planned. A feature of FloHet-2015 will be a series of plenary, invited lectures and a short course on fluorination and flow technology with new examples from the fine chemicals industry. For further information, to submit poster abstracts, and to register: http://www.arkat-usa.org/conferences-flohet-others/

Plenary lectures
Albert Padwa, Emory University, US Katritzky Memorial Lecture
Katritzky Memorial Lecture
Huw Davies, Emory University, US
Veronique Gouverneur, Oxford University, UK
Fluorine Chemistry: from Basic to Clinic
Timothy Jamison, MIT, US
Continuous Flow Multistep Synthesis
Peter Maienfisch, Syngenta, Switzerland
Christel Menet, Galapagos, Belgium
Tobias Ritter, Harvard University, US
Late-Stage Fluorination for PET Imaging
Paul Scola, BMS, US
Discovery of Asunaprevir (BMS-650032): An Approved NS3 Protease Inhibitor for the Treatment of HCV
Jay Siegel, Tianjin University, PRC
Aromatic Heterocyclic Compounds and Their Metal Complexes
Oliver Thiel, Amgen, US
Chemical Adventures with Small and Large Molecules
Yoshinori Yamamoto, Tohoku University, Japan
p-Conjugated Polycycles and Heterocycles through C-H and X-H Activation across Alkynes

Short Course
Graham Sandford, U. of Durham, UK
Selective Direct Fluorination Strategies: Batch and Flow

The use of organofluorine chemistry, fluorine gas in synthesis (including early failures), techniques for laboratory and manufacturing synthesis (batch and flow) and the current state of the art will be covered.

Invited Lecturers
Manfred Braun - Selective potassium channel openers with benzothiadiazine-, benzothiazole-, and isothiochromanone-skeletons
Craig Francis – Synthesis and Reactivity of the New Pyrazolo[1,5 b]thiatriazine Ring System
Phil Harris – Discovery of the Anti-Cancer Drug Votrient
Vakhid A. Mamedov – Ring Transformation Reactions of Quinoxalinones with “Outside” Group Participation
Victor Pike - Diaryliodonium Salts as Useful Precursors to Radiofluorinated Arenes and PET Radiotracers
Floris Rutjes – Organocatalytic Approaches to Biologically Relevant Heterocycles
Benjamin Sherry - Development of an Efficient Synthetic Route for HIV NNRTI Doravirine
Stephane Vincent - Synthesis of Fluorinated exo-Glycals and Furans Designed to Inhibit Bacterial Enzymes
Craig M. Williams - Natural Products from the Australian Rainforest
Chris Willis – Challenges in Natural Product Synthesis

Acceptances also have been received from: D. Ager (US); S. Arseniyadis (France); S. Ballet (Belgium); U. Beifuss (Germany); U. Bernier (US); C. Chung (US); J. Del Valle (US); L. Dias (Brazil); A. Dobbs (UK); T. Driver (US); L. El Kaim (France); P. Gois (Brazil); M. Gonzalez (US); U. Groselj (Slovenia); M. Huestis (US); Z. Janeba (Czech. Rep.); K. Laali, (US), M. Lakshman (US); J. Manchester (US); S. Mangelinckx (Belgium), A. E. Minatti (US); J. C. Monbaliu (Belgium); T.J.J. Mueller (Germany); F. Nagatsuji (Japan); A. Natarajan (Saudi Arabia); T. Opatz (Germany); T. Ozturk (Turkey); X. Pannecoucke (France); N. Peet (US); Z. Pei (US): G. Poda (Canada); R. Rieke (US); J. Ryan (Australia); K. Singh (India); K. Tehrani (Belgium); M. Tobisu; K. Toshiyuki (Japan); Y. Troin (France); E. van der Eycken (Belgium); J. van der Eycken (Belgium); M. Watson (US); G. Williams (Australia); L. Yet (US).

In collaboration with the Katritzky group at the University of Florida, CODESSA III is a state-of-the art QSAR/QSPR program that works directly with Semichem’s AMPAC to generate predictive models from quantum chemical, electrostatic and topological descriptors. If you are a past user of CODESSA, this completely rewritten product will blow you away! Every aspect of this product has been modernized and improved. Please visit www.semichem.com/codessa for details.

The printed edition of ARKIVOC (88 volumes) is available for the years 2000 - 2007 through www.Amazon.com. We do not plan to continue offering a printed edition of ARKIVOC, except by special arrangement. Please contact Eric Scriven efvs1@aol.com if you are interested in a printed edition.